@helle-devi - I still do not recommend Lepto vaccine. Too many Basenjis have had reaction to it. That said, if you are in an area with high issues with Lepto, you need to weigh averages. Lepto is typically found around standing water and usually from other dogs.... How much of an increase? Is your Basenji usually on leash? And if you decide to get the vaccine I would make sure it is separate from any other vaccines by at least two to three weeks. Then if you have a reaction you know it is from the Lepto shot. Also you should do Titer Test before giving shots (except Rabies since that is required by laws of each state). Many times doing a titer test will show that a dog is fully covered and do not need a booster. My C-Me will be 12 on Christmas Eve. She had her 1yr booster and never has needed one since. My Franie (will be 12 in January) needed a booster at age 9.
2008 Rabies Vaccine Adverse Reactions–JAVMA Report
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**2008 REPORT ON RABIES VACCINE ADVERSE REACTIONS IN DOGS
The Journal of the American Veterinary Medical Association has published a report in its April 1, 2008 issue, Vol. 232, No. 7, entitled: Postmarketing Surveillance of Rabies Vaccines for Dogs to Evaluate Safety and Efficacy."
Despite the extreme under-reporting of vaccinal adverse reactions, this report states on the second page that between April 1, 2004 and March 31, 2007, the Center for Veterinary Biologics, "nearly 10,000 adverse event reports (all animal species) were received by manufacturers of rabies vaccines….......Approximately 65% of the manufacturer's reports involved dogs."
The report further states on the second page that: "Rabies vaccines are the most common group of biological products identified in adverse event reports received by the CVB," and they give the following description of the adverse reaction followed by the % of dogs affected: Vomiting-28.1%, Facial Swelling-26.3%, Injection Site Swelling or Lump-19.4%, Lethargy-12%, Urticaria-10.1%, Circulatory shock-8.3%, Injection site pain-7.4%, Pruritus-7.4%, Injection site alopecia or hair loss-6.9%, Death-5.5%, Lack of Consciousness-5.5, Diarrhea-4.6%, Hypersensitivity (not specified)-4.6%, Fever-4.1%, Anaphylaxis-2.8%, Ataxia-2.8%, Lameness-2.8%, General signs of pain-2.3%, Hyperactivity-2.3%, Injection site scab or crust-2.3%, Muscle tremor-2.3%, Tachycardia-2.3%, and Thrombocytopenia-2.3%.
Veterinarians are not required by law to report adverse reactions to vaccines, to which the World Small Animal Veterinary Association stated in their 2007 Vaccine Guidelines that there is: "gross under-reporting of vaccine-associated adverse events which impedes knowledge of the ongoing safety of these products," and in an article entitled, A New Approach to Reporting Medication and Device Adverse Effects and Product Problems, (JAMA - June 2, 1993. Vol.269, No.21. p.2785) Dr. David Kessler, former head of the Food & Drug Administration, reported that "only about 1% of serious events are reported to the FDA."
In light of the 10,000 adverse reactions to the rabies vaccine in the JAVMA report, 65% of which were in dogs, the estimated 1% reporting of "serious" events by the former head of the FDA means that the actual number of dogs that had adverse reactions to the vaccine would be more like 650,000!!!!!
World Small Animal Veterinary Association 2007 Vaccine Guidelines http://www.wsava.org/SAC.htm Scroll down to Vaccine Guidelines 2007 (PDF)
A New Approach to Reporting Medication and Device Adverse Effects and Product Problems http://www.vaccinationnews.com/Adverse_Reactions/VAERS/credible_estimates.htm Scroll down to David Kessler statement in JAMA - June 2, 1993,vol.269, No.21, p.2785
Animal Wellness Magazine Article Vol. 8 Issue 6, How Often Does he REALLY Need A Rabies Shot Animal Wellness Magazine - devoted to natural health in animals
Rabies Shot Killed my Poodle May 28, 2008 Channel 5 News WCVB http://www.thebostonchannel.com:80/news/16410586/detail.html?rss=bos&taf=bos
The Rabies Challenge Animal Wise Radio Interview
Listen to Animal Wise (scroll down to The Rabies Challenge 12/9/07)The Vaccine Challenge Animal Talk Naturally Online Radio Show » The Vaccine Challenge - Show #91
US Declared Canine-Rabies Free – CDC Announces at Inaugural World Rabies Day Symposium CDC Press Release - September 7, 2007
Rabies Prevention – United States, 1991 Recommendations of the Immunization Practices Advisory Committee (ACIP), Center for Disease Control's Morbidity and Mortality Weekly March 22, 1991 / 40(RR03);1-19 http://www.cdc.gov/mmwr/preview/mmwrhtml/00041987.htm "A fully vaccinated dog or cat is unlikely to become infected with rabies, although rare cases have been reported (48). In a nationwide study of rabies among dogs and cats in 1988, only one dog and two cats that were vaccinated contracted rabies (49). All three of these animals had received only single doses of vaccine; no documented vaccine failures occurred among dogs or cats that had received two vaccinations. "**
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Channel 5 News WCVB Woman: Rabies Shot Killed my Poodle
May 28, 2008 http://www.thebostonchannel.com:80/news/16410586/detail.html?rss=bos&taf=bos -
Arkansas Veterinary Medical Association http://www.arkvetmed.org/new.html
RABIES VACCINATIONS
New RecommendationsRecommendations for maintaining adequate pre-exposure immunization status: A routine booster every two years is NOT recommended since the newer cell culture vaccines often confer adequate antibody levels for 5 to 8 years and risk of adverse reactions is increased by frequent boosters. The standard pre-exposure recommendation for veterinarians practicing in an area with enzootic rabies is serologic testing every two years with booster vaccination when the antibody titer falls below the acceptable level, i.e. 1:5 by RFFIT.
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Vaccinal adverse reactions are becoming more recognized and acknowledged in the veterinary community – in an August 1, 2008 article in DVM360 entitled Vaccination: An Overview, http://veterinarycalendar.dvm360.com/avhc/article/articleDetail.jsp?id=568351 Dr. Melissa Kennedy states that of the two types of vaccinal adverse reactions:
Adverse reactions have also become a major concern in small animal medicine. …. These fall into two general categories. The first is immediate hypersensitivity. This may be a local or systemic response, and is due to pre-existing antibody to the agent. This is the classic "allergic reaction" to the vaccine and can be life-threatening. The second is a delayed response, requiring days of longer to develop. The vaccine, seen as foreign, elicits a significant inflammatory response and is especially true for adjuvanted vaccines. This response can manifest as a granuloma, or more seriously, a fibrosarcoma .
Further, she reports that The likelihood of adverse reactions in dogs has been found to correlate with the size of the dog and the number of inoculations given, with higher risk associated with small size and multiple inoculations.
Duration of Immunity to Canine Vaccines: What We Know and Don't Know, Dr. Ronald Schultz http://www.cedarbayvet.com/duration_of_immunity.htm
What Everyone Needs to Know about Canine Vaccines, Dr. Ronald Schultz
http://www.puliclub.org/CHF/AKC2007Conf/What%20Everyone%20Needs%20to%20Know%20About%20Canine%20Vaccines.htmVaccination: An Overview Dr. Melissa Kennedy, DVM360 http://veterinarycalendar.dvm360.com/avhc/article/articleDetail.jsp?id=568351
World Small Animal Veterinary Association 2007 Vaccine Guidelines http://www.wsava.org/SAC.htm Scroll down to Vaccine Guidelines 2007 (PDF)
The 2003 American Animal Hospital Association's Canine Vaccine Guidelines are accessible online at http://www.leerburg.com/special_report.htm .
The 2006 American Animal Hospital Association's Canine Vaccine Guidelines are downloadable in PDF format at http://www.aahanet.org/PublicDocumen…s06Revised.pdf .
Veterinarian, Dr. Robert Rogers,has an excellent presentation on veterinary vaccines at http://www.newvaccinationprotocols.com/
Duration of Immunity: The Rabies Vaccine Challenge - Show #185 Animal Talk Radio Show 7/30/08 http://www.blogtalkradio.com/animaltalknaturally/2008/07/30/Duration-of-Immunity-The-Rabies-Vaccine-Challenge-Show-186
October 1, 2002 DVM Newsletter article entitled, AVMA, AAHA to Release Vaccine Positions, http://www.dvmnewsmagazine.com/dvm/article/articleDetail.jsp?id=35171
July 1, 2003 DVM Newsletter article entitled, What Do We Tell Our Clients?, Developing thorough plan to educate staff on changing vaccine protocols essential for maintaining solid relationships with clients and ensuring quality care http://www.dvmnewsmagazine.com/dvm/article/articleDetail.jsp?id=61696
July 1, 2003, DVM Newsletter article, Developing Common Sense Strategies for Fiscal Responsibility: Using an interactive template to plan service protocol changes http://www.dvmnewsmagazine.com/dvm/article/articleDetail.jsp?id=61694
Animal Wellness Magazine Article Vol. 8 Issue 6, How Often Does he REALLY Need A Rabies Shot Animal Wellness Magazine - devoted to natural health in animals
The Rabies Challenge Animal Wise Radio Interview
Listen to Animal Wise (scroll down to The Rabies Challenge 12/9/07)The Vaccine Challenge Animal Talk Naturally Online Radio Show ? The Vaccine Challenge - Show #91
Rabies Shot Killed my Poodle May 28, 2008 Channel 5 News WCVB http://www.thebostonchannel.com:80/news/16410586/detail.html?rss=bos&taf=bos
US Declared Canine-Rabies Free – CDC Announces at Inaugural World Rabies Day Symposium CDC Press Release - September 7, 2007
Rabies Prevention – United States, 1991 Recommendations of the Immunization Practices Advisory Committee (ACIP), Center for Disease Control's Morbidity and Mortality Weekly March 22, 1991 / 40(RR03);1-19 http://www.cdc.gov/mmwr/preview/mmwrhtml/00041987.htm "A fully vaccinated dog or cat is unlikely to become infected with rabies, although rare cases have been reported (48). In a nationwide study of rabies among dogs and cats in 1988, only one dog and two cats that were vaccinated contracted rabies (49). All three of these animals had received only single doses of vaccine; no documented vaccine failures occurred among dogs or cats that had received two vaccinations. "
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Judy Schor's agility champion, Peaches, suffered a significant adverse reaction to a rabies booster. Judy has posted photos of Peaches and a letter from the vaccine manufacturer, Fort Dodge, offering a settlement to pay for medical treatment if they not disclose information about the claim. You can read the letter and see photos of Peaches at this link: http://www.facebook.com/album.php?aid=2042916&id=1447415540&ref=mf .
