My Isis hated them too, at first, Then we both got better, I got very quick, grab, jab, and gone! I used the area at the neck and shoulders (where you put Advantage) and just pinched up skin, stuck her and injected. I am a nurse, so giving a shot is easy for me, but giving one to a wiggling dog that yelped was hard at first, and I had a human helper. After a few months, I think that area got a bit numb and that helped. You may have to muzzle, then get over him, clamp him between your legs, facing forward, and go for it. Then reward instantly with a bit of chicken or something wonderful. It is a lot harder than having to give pills, but with patience and practice, you will find a way that works for you. Good luck, I am thinking of you,
Anne in Tampa