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Fancoi Syndrom Information

Basenji Health Issues & Questions
  • Hi Sharron!

    I found information about the test to the Fanconi Syndrom and not all the information i was looking for.

    But thank you anyway!

    Hila

  • If you didn't get forwarded here, you should check this out too: http://www.basenjiclub.com/?q=node/64

  • What else do you need to know?

  • I would like to know what is the Fanconi Syndrom? why does it happens? what are the symptoms? treatment?

    Thanks again,
    Hila

  • Please go also to www.basenjihealth.org

  • @etzbseder:

    The shortest and simplest way to describe it is a mutated form of diabetes. BUT remember that is the shortest, far from the best and most accurate. It just gets the laymans version of it out there enough to get the mind going.

    It it really NOT a mutated form of diabetes. Diabetes is sugar in the blood, Fanconi is sugar in the urine and NOT in the blood… Often confused, but totally different

  • @tanza:

    It it really NOT a mutated form of diabetes. Diabetes is sugar in the blood, Fanconi is sugar in the urine and NOT in the blood… Often confused, but totally different

    Thanks, Tanza… I almost replied to that one also, but my answer got way too long and detailed, so I junked it. LOL

    I think that because Fanconi is often mis-diagnosed as Diabetes it is of utmost importance to NEVER confuse the two. Fanconi is a disease of the kidneys; Diabetes is a disease of the pancreas. While both do inhibit the body's ability to absorb nutrients, they are NOT RELATED to one another.

  • Fanconi Syndrome is renal tubular dysfunction, the kidneys of an affected dog become ineffective at reabsorbing the nutrients that body needs and the dog then spills those nutrients in its urine. The easiest of the nutrients lost to test for is sugar hence the testing of urine for glucose but the reality is that Faconi dogs spill many nutrients including protein, glucose, vitamins, and minerals.

    Symptoms include increased thirst, increased urination, spilling of sugar in the urine, and abnormal blood gas results. Fanconi is caused by a defective gene and is recessive in its inheritance pattern. There is now a gene marker test available for Fanconi Syndrome so there is no reason that a Fanconi Affected puppy ever be born. It can be prevented by testing the parents prior to breeding and making sure that at least one of the parents has tested clear for the disorder.

  • Thank you so much for the information Ivoss!
    You helped me a lot!

    Hila

  • Can someone tell me how long it takes to get the results of the Fanconi DNA testing done at the Vet. hospital? It has been about 6 wks. since I sent Sahara's blood in and they cashed my check last month.

  • It has been taking about 3 weeks or so for most people. You can check with the lab and see what is taking so long. There is a phone number for Liz Hansen on this page, http://www.canine-epilepsy.net/Docs/DNAhowto.html

    She should be able to answer your question.

  • Hey I have been waiting for one for 9wks now… so ... who knows..

  • If you have been waiting a long time for results it may be worthwhile to call and ask. The lab had results for one of mine but it somehow had gotten lost between the lab and the report. They got me my results and then it took me over 3 months to get the OFA certificate and have it posted on the OFA site.

  • @lvoss:

    If you have been waiting a long time for results it may be worthwhile to call and ask. The lab had results for one of mine but it somehow had gotten lost between the lab and the report. They got me my results and then it took me over 3 months to get the OFA certificate and have it posted on the OFA site.

    Been there done that… with no results also... at least "yet".... somethings are just meant to drive you nuts!

  • Well, I called and it seems Sahara is affected. Does that mean she will get the Fanconi or has a greater chance of getting it? I hate this but at least I know to make sure I start testing. Will giving her vitamine supplements help her now, and do I need Pet Insurance for all the testing that will probably be done if she does get Fanconi. Help!

  • This means that she most likely has two copies of the gene for Fanconi Syndrome and will most likely become symptomatic at some point in her life. The age of onset can vary greatly. Some become symptomatic very early and some not until much later. There are currently 2 dogs that have tested as Probably Affected and are not symptomatic at over 10 years of age but this is a rare occurrence. Pet insurance will probably not cover the expenses related to treating Fanconi Syndrome but you will need to research to see for sure.

    Try strip testing a few days in a row each month since in the early stages dogs may spill sugar intermittently.

  • Sahara will be 2 in Jan. will I need to start the strip testing that early, also will vitamins help now. Thanks

  • @youngandtired:

    Well, I called and it seems Sahara is affected. Does that mean she will get the Fanconi or has a greater chance of getting it? I hate this but at least I know to make sure I start testing. Will giving her vitamine supplements help her now, and do I need Pet Insurance for all the testing that will probably be done if she does get Fanconi. Help!

    I am so sorry to hear that…. how old is Sahara? You should, if you have not been, strip testing her monthly and for a few days in a row. The earlier that you catch Fanconi, usually the better they respond to treatment. There is really nothing at this time that you can do, other then to keep her as healthy as possible... You should also print off the protocol and give to your Vet for her file. You can find it on the BCOA site www.basenji.org

    Another thing to be prepared, you might want to ask your Vet if they do blood gases and if not were is the closes place that does. Never hurts to be proactive just in case.

    And again as Lisa points out, onset of Fanconi can been at a number of different ages… from 3 to 12....

  • @youngandtired:

    Sahara will be 2 in Jan. will I need to start the strip testing that early, also will vitamins help now. Thanks

    If she were mine, I would start now. And there is no real knowledge what might or might not help, but vitamins can't hurt, I wouldn't think. Remember that until last year we didn't have a test and therefore people didn't have the knowledge that their Basenji was predisposed for Fanconi.. they just strip tested and knew that they started to spill sugar in the urine.

    Do you have pedigree information on Sahara? I don't remember where you got her.

  • Oh, I am so very sorry your b came back affected.
    BUT I do know of a great fanconis support group.
    So, when you first see the b is spilling sugar, do let us know and I will give you the contact info.
    Seems that they do not take in folks/dogs who have not yet started to show the signs of fanconis.
    But rest assured that there is help out there for you and yours.
    Hugs.
    Remember, you dog doesn't know it might be sick.
    So, just take your clue for living each day at a time.
    Hugs again.

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    She still seeks out water but not to the degree that she was. As the accidents wane, I have been trying to leave the water out a bit more, but like one of the other members said about their husband, mine also is sick of cleaning up the pee so I have to find a happy medium between the two. All in all I think we are doing fine, and once again thanks for all of your concern. I will be sure to connect with the Basenji Forums again if there are any other questions.