when my puppy was teething I would stop up one end with just a dab of peanut butter, fill the rest with water and freeze it. He LOVED it. You could let them play with it outside, but really I diddnt find it too messy even for the house. The ice melts at about the rate the dog licks at it, and the little dribbles are easy enough just to mop up after. I have also put in chunks of apple (no core or seeds) or baby carrots. I also have added peanut butter from time to time. I just throw it in the dishwasher afterwards to clean it. Kong makes treats to go inside as well.
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