Responding to lovemybaroo, the lump at your Basenji's vaccination site could be from the adjuvants used in "killed" vaccines (such as Lyme, Leptospira, Rabies). Adjuvants are components (sometimes aluminum)added to killed vaccines to enhance the immunological response and they do cause inflammation at the vaccination site.
Giving your dog multiple vaccinations at once not only increases the risk of adverse reactions, it also increases the risk of the vaccines neutralizing each other and negating or lowering the immunological response (see quote below). According to all the data I've read, it is better to give the shots separately with a space of about 2-3 weeks in between.
There is also information below on kennel cough (bordetella) that might interest you.
On Page 16 of the 2003 AAHA Guidelines under Immunological Factors Determining Vaccine Safety, it states that: "Although increasing the number of components in a vaccine may be more convenient for the practitioner or owner, the likeli-hood for adverse effects may increase. Also, interference can occur among the components. Care must be taken not to administer a product containing too many vaccines simultaneously if adverse events are to be avoided and opti-mal immune responses are sought. "
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Regarding the Bordetella (Kennel Cough) vaccine, on Page 2 of the American Animal Hospital Association's 2003 Canine Vaccine Guidelines and Recommendations, it states that "Optional or 'noncore' vaccines are those that the committee believe should be considered only in special circumstances because their use is more dependent on the exposure risk of the individual animal. Issues of geographic distribution and lifestyle should be considered before administering these vaccines. In addition, the diseases involved are generally self-limiting or respond readily to treatment. The committee believes this group of vaccines comprises distemper-meases virus (D-MV), canine parainfluenza virus (CPIV), Leptospira spp., Bordetella bronchispetica, and Borrelia burdorferi."
Further, on Page 14 of the AAHA Guidelines, it states: "Bordetella bronchiseptica (B. bronchiseptica): Bordetella bronchiseptica is another cause of the “kennel cough” syn-drome. Infection in some susceptible dogs generally causes a self-limiting, upper respiratory disease and rarely causes life-threatening disease in otherwise healthy animals. Clini-cal disease resolves quickly when treated with appropriate antibiotics. Vaccination does not block infection but appears to lessen clinical disease, and vaccines provide a short DOI (<1 year) http://www.cedarbayvet.com/duration_of_immunity.htmhttp://www.leerburg.com/special_report.htmhttp://www.aahanet.org/PublicDocumen…s06Revised.pdfhttp://www.newvaccinationprotocols.com/
