I used Rescue Remedy for my stress, my roommate has a spray she sprays on her dogs butt when he chews it raw to make him stop, I think she's doing it wrong, but whatever, not my dog to worry about
Bindi has only gotten car sick once, and it was because it was really hot (Florida here) and she had just eaten (bad idea on my part) and wouldn't sit still so she got jerked around a lot
I find it helps to talk to her, pet her, calm her down, crack the windows or throw on the AC, play soft music (at least Bindi likes soft music) I also gives her treats when she sits and lays down which distracts her
most of the time she wants to just sit in my lap, but she can't because I am driving
(P.S. I drive a stick by myself, so keeping her at bay, petting, making her sit, feeding her treats, etc. all while shifting is an ordeal LOL I need to get her a seat belt)
P.P.S. Peppermint and Ginger are two good natural remedies for an upset stomach, if you can find a way for the dog to ingest them, it should help too
~Kat