This is a late answer but for someone who might read this in the future we will post it anyway. The risk is much higher to the animal and it certainly raises the risk the animal bleeding out. There is also more swelling. We were going to have our Show Basenji spayed this year. She went into heat slightly early and our vet said that we should wait until after the heat was over before he felt comfortable doing the spay for the reasons mentioned.
Spaying while in heat
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My 7 month old girl has just come into her 1st season. She lives with 2 neutered male dogs(not Basenjis) and so far they're leaving her alone. I've booked her in for spaying in 3 days time. What do others think? Should I let her finish this heat cycle and get her done later?
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The advice we have been given and that we followed is this: spaying exactly between two heats, because at that point she is in a balanced hormonal state. To spay her now would put her system off balance. I would strongly recommend you cancel the meeting and wait at least 4 months or so.
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Most Vets will not recommend spay during season and unless there is a medical reason for doing it now, will recommend waiting till she is at least 3 to 4 weeks past the end of her season. I would also agree you should put it off and wait. Keep in mind however the neutered males can achieve a tie with a bitch in season, however considered "safe sex"… but since you have two males, this could present a problem, so something to keep an eye on